{"id":20413,"date":"2024-04-11T08:00:00","date_gmt":"2024-04-11T13:00:00","guid":{"rendered":"https:\/\/naturalwomanhood.org\/?p=20413"},"modified":"2026-04-22T07:50:36","modified_gmt":"2026-04-22T12:50:36","slug":"%d0%bf%d1%80%d0%b8%d1%87%d0%b8%d0%bd%d0%b0-%d1%83%d1%82%d1%80%d0%b5%d0%bd%d0%bd%d0%b5%d0%b9-%d1%82%d0%be%d1%88%d0%bd%d0%be%d1%82%d1%8b","status":"publish","type":"post","link":"https:\/\/naturalwomanhood.org\/ru\/morning-sickness-cause\/","title":{"rendered":"\u0427\u0442\u043e \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u0443\u0442\u0440\u0435\u043d\u043d\u044e\u044e \u0442\u043e\u0448\u043d\u043e\u0442\u0443 (\u0438 \u0433\u0438\u043f\u0435\u0440\u0435\u043c\u0435\u0437\u0438\u0441 \u0433\u0440\u0430\u0432\u0438\u0434\u0430\u0440\u0443\u043c)?"},"content":{"rendered":"\n

\u201cHey y\u2019all, just found out I\u2019m five weeks pregnant. Definitely a welcome pregnancy, it\u2019s my first, but I have emetophobia [fear of vomiting] and have had constant anxiety about the impending morning sickness literally since I saw that first positive test.\u201d<\/em>\u00a0<\/p>\n\n\n\n

In response to this Reddit post<\/a> from April 2023, a chorus of well wishers shared their experiences and compared their own symptoms to their mothers\u2019 and sisters\u2019. The range of responses attested to the unpredictability of \u201cmorning sickness\u201d\u2014the nausea, vomiting, and food aversion that define early pregnancy for many women but inexplicably leave others untouched. Here\u2019s the frustrating reality: despite its high prevalence among expecting women, historically, no one has known what causes morning sickness. And because no one has known what causes it, treatments for morning sickness have been rather thin on the ground.\u00a0<\/p>\n\n\n\n

But all that could be changing, thanks to a 2023 study by Cambridge University [1]. Researchers found that the hormone \u201cgrowth differentiation factor 15\u201d (GDF15<\/em>) plays a major role in morning sickness. Even more helpful, researchers discovered that women can become immune to GDF15\u2019s<\/em> effects through exposure to the hormone before<\/em> pregnancy. Major news outlets such as The New York Times<\/em> celebrated<\/a> the discovery as a helpful breakthrough for women everywhere, and expressed hope it could lead to the development of better morning sickness treatments.<\/p>\n\n\n\n

Nausea and vomiting in pregnancy (NVP), aka morning sickness, vs. hyperemesis gravidarum<\/span><\/h2>\n\n\n\n

At least half<\/a> of pregnant women experience symptoms of nausea and vomiting in pregnancy (NVP), known colloquially as \u201cmorning sickness.\u201d As countless women can verify, \u201cmorning sickness\u201d is a bit of a misnomer since the symptoms can occur at any time of day. In most cases, morning sickness symptoms disappear around the end of the first trimester. For between 0.3% and 18% of women, however, the symptoms are both severe and<\/em> last throughout the entire pregnancy [2]. This condition is known as hyperemesis gravidarum (HG). Until very recently, the underlying causes of morning sickness and HG were considered a mystery by the medical community.\u00a0<\/p>\n\n\n\n

The connection between GDF15<\/em>, morning sickness, and hyperemesis gravidarum <\/span><\/h2>\n\n\n\n

The major breakthrough from the 2023 Cambridge study involves a hormone called GDF15<\/em>, and it\u2019s normally present in low levels in men and non-pregnant women. On the average day, GDF15 <\/em>helps the body adapt to cellular stress caused by low oxygen levels, cigarette smoking, endurance exercise<\/a> and more [1][6]. Increased GDF15<\/em> levels actually lower<\/em> inflammation.\u00a0<\/p>\n\n\n\n

GDF15<\/em> is also well known as an important factor in appetite suppression and weight loss. Metformin, commonly prescribed to treat diabetes<\/a> (as well as polycystic ovary syndrome<\/a>), increases GDF15 <\/em>levels [7]. Researchers first discovered GDF15<\/em> back in 2000 and observed that it was naturally high in pregnant women [3].<\/p>\n\n\n\n

Later research found that women with hyperemesis gravidarum had much higher levels of GDF15<\/em> than women who didn\u2019t experience HG, and other research determined that high levels of GDF15 <\/em>come mostly from the baby (in its trophoblastic stage of development) rather than from the mother [4][5]. Prior to the 2023 Cambridge study though, research couldn\u2019t definitively answer whether higher GDF15<\/em> levels lead to HG or are caused by it.  <\/p>\n\n\n\n

Cambridge research: High GDF15<\/em> levels cause morning sickness and HG <\/span><\/h3>\n\n\n\n

After studying over 18,000 participants, the 2023 Cambridge research team similarly found that GDF15<\/em> is higher in women who have nausea and vomiting of pregnancy or hyperemesis gravidarum, compared to pregnant women who have neither. They also confirmed that high GDF15<\/em> levels actually cause <\/em>NVP and HG. <\/p>\n\n\n\n

Most surprisingly, the researchers found that higher levels of circulating GDF15<\/em> p<\/em>rior to pregnancy were associated with reduced <\/em>risk of HG and morning sickness. This suggests that women can become desensitized to the effects of GDF15<\/em>, and not suffer from morning sickness or HG, if they\u2019ve had previous exposure before getting pregnant. This makes sense, since the surge of GDF15<\/em> happens in all pregnant women, but not all pregnant women experience morning sickness and very few, by the numbers, suffer hyperemesis gravidarum. <\/p>\n\n\n\n

The Cambridge researchers concluded that fetal-produced GDF15 only<\/em> triggers a response in women who weren\u2019t sufficiently desensitized to GDF15 \u2018s <\/em>effects before pregnancy. Since 75% of women who experience HG in one pregnancy will experience it in later pregnancies, it might mean that GDF15<\/em> desensitization is crucial before the first<\/em> pregnancy a woman has. <\/p>\n\n\n\n

Mice research mimics the surge of GDF15<\/em> that happens during pregnancy<\/span><\/h3>\n\n\n\n

To mimic the natural elevation in GDF15<\/em> during pregnancy, the Cambridge study included a mice testing component to see whether previous GDF15 <\/em>exposure could lead to less nausea and vomiting at higher doses. Researchers found that exposure to small amounts of GDF15 <\/em>prevented symptoms of food aversion and weight loss due to vomiting when the mice were given a larger dose of the hormone. The smaller initial dose effectively made the rats immune to the effects of the larger dose later on.  <\/p>\n\n\n\n

Women with GDF15 exposure before pregnancy are less likely to suffer morning sickness<\/span><\/h3>\n\n\n\n

The Cambridge study also studied whether non-pregnant women with abnormally high levels of GDF15 <\/em>were protected from NVP and HG once they became pregnant. The researchers conducted a subanalysis on a group of women with \u03b2-thalassaemia, a rare blood disorder that causes higher-than-average amounts of GDF15<\/em> in the body [1]. When these women became pregnant, only about 5% experienced NVP. This is far less than the 60% of women in the control group (who didn\u2019t have the blood disorder) who experienced morning sickness.<\/p>\n\n\n\n

How does this new knowledge about the cause of morning sickness help us better treat it?<\/span><\/h2>\n\n\n\n

The Cambridge researchers opined, \u201cThe fact that high GDF15<\/em> levels in the non-pregnant state appear to protect against the development of NVP and HG suggests that strategies which safely increase circulating GDF15<\/em> levels before pregnancy may be useful in the prevention of these conditions.\u201d And for those wondering about the safety of GDF15<\/em> as a possible treatment for morning sickness, the researchers had the following to say: \u201cThe safety of recombinant GDF15<\/em>, at least in the short term and outside of pregnancy, has been demonstrated in Phase 1 clinical trials and this could be administered at low doses before pregnancy with the intention of inducing GDF15\/GFRAL<\/em> desensitization.\u201d <\/p>\n\n\n\n

What about Metformin?<\/span><\/h3>\n\n\n\n

Remember how I mentioned diabetes and PCOS drug Metformin\u2019s effect on GDF15 <\/em>above? The researchers suggested, \u201cAlternatively, metformin robustly increases GDF15<\/em> in humans and could be tested as a prophylactic agent for HG,\u201d but acknowledged that Metformin given to women with gestational diabetes might slow down fetal growth. <\/p>\n\n\n\n

The bottom line on the cause of morning sickness<\/span><\/h2>\n\n\n\n

Now that we know what causes morning sickness, more research is needed to learn how we can safely prevent it. Given how much HG can impact both the mom and the preborn baby\u2019s health, researchers should prioritize exploration of whether desensitization in between pregnancies (whether with Metformin or GDF15<\/em> or something else) could prevent repeat HG. Researchers also need to determine what medications can safely be given to non-pregnant women to desensitize them before conceiving, as well as whether anything can safely be given during pregnancy to treat HG. <\/p>\n\n\n\n

References:<\/p>\n\n\n\n[1] Fejzo, M., Rocha, N. et al. \u201cGDF15 linked to maternal risk of nausea and vomiting during pregnancy.\u201d Nature <\/em>(2023). https:\/\/doi.org\/10.1038\/s41586-023-06921-9.<\/p>\n\n\n\n[2] Fejzo, M., Trovik, J., et al. \u201cNausea and vomiting of pregnancy and hyperemesis gravidarum.\u201d Nat Rev Dis Primers<\/em>. 2019 Sep 12;5(1):62. doi: 10.1038\/s41572-019-0110-3. PMID: 31515515. <\/p>\n\n\n\n[3] A. G. Moore, D. A. Brown, W. D. Fairlie, A. R. Bauskin, P. K. Brown, M. L. C. Munier, P. K. Russell, L. A. Salamonsen, E. M. Wallace, S. N. Breit, The Transforming Growth Factor-\u03b2 Superfamily Cytokine Macrophage Inhibitory Cytokine-1 Is Present in High Concentrations in the Serum of Pregnant Women, The Journal of Clinical Endocrinology & Metabolism<\/em>, Volume 85, Issue 12, 1 December 2000, Pages 4781\u20134788, https:\/\/doi.org\/10.1210\/jcem.85.12.7007<\/a><\/p>\n\n\n\n[4] Fejzo MS, Sazonova OV, Sathirapongsasuti JF, Hallgr\u00edmsd\u00f3ttir IB, Vacic V, MacGibbon KW, Schoenberg FP, Mancuso N, Slamon DJ, Mullin PM; 23andMe Research Team. Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum. Nat Commun. 2018 Mar 21;9(1):1178. doi: 10.1038\/s41467-018-03258-0. PMID: 29563502; PMCID: PMC5862842.<\/p>\n\n\n\n[5] Turco, M. Y. et al. Trophoblast organoids as a model for maternal-fetal interactions during human placentation. Nature<\/em> 564, 263\u2013267 (2018).<\/p>\n\n\n\n[6] Wang, D., Day, E.A., Townsend, L.K. et al.<\/em> \u201cGDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease.\u201d Nat Rev Endocrinol<\/em> 17, 592\u2013607 (2021). https:\/\/doi.org\/10.1038\/s41574-021-00529-7.[7] Gerstein, Hertzel C et al. \u201cGrowth Differentiation Factor 15 as a Novel Biomarker for Metformin.\u201d Diabetes care<\/em> vol. 40,2 (2017): 280-283. doi:10.2337\/dc16-1682.<\/p>\n\n\n\n

Additional Reading:<\/p>\n\n\n\n

Is your pregnancy diet up to date with science?<\/a><\/p>\n\n\n\n

Caffeine, alcohol, and tobacco products during pregnancy: What we know (and what we don’t)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"\u041a\u0435\u043c\u0431\u0440\u0438\u0434\u0436\u0441\u043a\u0438\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442, \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e, \u0440\u0435\u0448\u0438\u043b \u0432\u043e\u043f\u0440\u043e\u0441, \u0441\u0442\u0430\u0440\u044b\u0439 \u043a\u0430\u043a \u0432\u0440\u0435\u043c\u044f","protected":false},"author":99,"featured_media":20414,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","csco_singular_sidebar":"","csco_page_header_type":"","csco_page_load_nextpost":"","csco_post_video_location":[],"csco_post_video_url":"","csco_post_video_bg_start_time":0,"csco_post_video_bg_end_time":0,"footnotes":""},"categories":[5185,5352],"tags":[6155],"class_list":{"0":"post-20413","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-pregnancy-childbirth","8":"category-pregnancy-health","9":"tag-morning-sickness-2","10":"cs-entry","11":"cs-video-wrap"},"acf":[],"yoast_head":"\nWhat causes morning sickness (and hyperemesis gravidarum)? - Natural Womanhood<\/title>\n<meta name=\"description\" content=\"Why do some women get so sick in the 1st trimester+? A hormone called GDF15 causes morning sickness and hyperemesis gravidarum, study finds.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/naturalwomanhood.org\/ru\/\u043f\u0440\u0438\u0447\u0438\u043d\u0430-\u0443\u0442\u0440\u0435\u043d\u043d\u0435\u0439-\u0442\u043e\u0448\u043d\u043e\u0442\u044b\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What causes morning sickness (and hyperemesis gravidarum)?\" \/>\n<meta property=\"og:description\" content=\"Cambridge University may have solved a question as old as time\" \/>\n<meta property=\"og:url\" content=\"https:\/\/naturalwomanhood.org\/ru\/\u043f\u0440\u0438\u0447\u0438\u043d\u0430-\u0443\u0442\u0440\u0435\u043d\u043d\u0435\u0439-\u0442\u043e\u0448\u043d\u043e\u0442\u044b\/\" \/>\n<meta property=\"og:site_name\" content=\"Natural Womanhood\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NaturalWomanhood\" \/>\n<meta property=\"article:published_time\" content=\"2024-04-11T13:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-22T12:50:36+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jasmine Adams Piescik\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@naturwomanhood\" \/>\n<meta name=\"twitter:site\" content=\"@naturwomanhood\" \/>\n<meta name=\"twitter:label1\" content=\"\u041d\u0430\u043f\u0438\u0441\u0430\u043d\u043e \u0430\u0432\u0442\u043e\u0440\u043e\u043c\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jasmine Adams Piescik\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u041f\u0440\u0438\u043c\u0435\u0440\u043d\u043e\u0435 \u0432\u0440\u0435\u043c\u044f \u0434\u043b\u044f \u0447\u0442\u0435\u043d\u0438\u044f\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 \u043c\u0438\u043d\u0443\u0442\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/\"},\"author\":{\"name\":\"Jasmine Adams Piescik\",\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/person\/1d349d0b11b6928f0f91db832397c929\"},\"headline\":\"What causes morning sickness (and hyperemesis gravidarum)?\",\"datePublished\":\"2024-04-11T13:00:00+00:00\",\"dateModified\":\"2026-04-22T12:50:36+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/\"},\"wordCount\":1447,\"commentCount\":2,\"publisher\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg\",\"keywords\":[\"morning sickness\"],\"articleSection\":[\"Pregnancy & Childbirth\",\"Pregnancy Health\"],\"inLanguage\":\"ru-RU\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/\",\"url\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/\",\"name\":\"What causes morning sickness (and hyperemesis gravidarum)? - Natural Womanhood\",\"isPartOf\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg\",\"datePublished\":\"2024-04-11T13:00:00+00:00\",\"dateModified\":\"2026-04-22T12:50:36+00:00\",\"description\":\"Why do some women get so sick in the 1st trimester+? A hormone called GDF15 causes morning sickness and hyperemesis gravidarum, study finds.\",\"breadcrumb\":{\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#breadcrumb\"},\"inLanguage\":\"ru-RU\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ru-RU\",\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage\",\"url\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg\",\"contentUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg\",\"width\":2560,\"height\":1707,\"caption\":\"molar pregnancy, incomplete molar pregnancy, partial molar pregnancy, complete molar pregnancy, signs of molar pregnancy, molar pregnancy cancer\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/naturalwomanhood.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"What causes morning sickness (and hyperemesis gravidarum)?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/naturalwomanhood.org\/#website\",\"url\":\"https:\/\/naturalwomanhood.org\/\",\"name\":\"Natural Womanhood\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/naturalwomanhood.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ru-RU\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/naturalwomanhood.org\/#organization\",\"name\":\"Natural Womanhood\",\"url\":\"https:\/\/naturalwomanhood.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ru-RU\",\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Natural Womanhood\"},\"image\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/NaturalWomanhood\",\"https:\/\/x.com\/naturwomanhood\",\"https:\/\/www.instagram.com\/naturalwomanhood\/\",\"https:\/\/www.linkedin.com\/company\/natural-womanhood\/\",\"https:\/\/www.youtube.com\/channel\/UCt5gjuXYioYkx31Iq4tHLGg\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/person\/1d349d0b11b6928f0f91db832397c929\",\"name\":\"Jasmine Adams Piescik\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ru-RU\",\"@id\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/jasmine-scaled.jpg\",\"url\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/jasmine-scaled.jpg\",\"contentUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/jasmine-scaled.jpg\",\"caption\":\"Jasmine Adams Piescik\"},\"description\":\"Jasmine Piescik became fascinated with fertility awareness and natural women\u2019s health during college through conversations with other women, her own struggles with hormonal imbalances, and a long journey of learning to appreciate the gift of her own body. She now lives with her husband in Charlottesville, VA, where she is pursuing her Master's in English and enjoys hiking, trying new recipes, and exploring the local array of coffee shops and wineries.\",\"url\":\"https:\/\/naturalwomanhood.org\/ru\/author\/jadams\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"\u0427\u0442\u043e \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u0443\u0442\u0440\u0435\u043d\u043d\u044e\u044e \u0442\u043e\u0448\u043d\u043e\u0442\u0443 (\u0438 \u0433\u0438\u043f\u0435\u0440\u0435\u043c\u0435\u0437\u0438\u0441 \u0433\u0440\u0430\u0432\u0438\u0434\u0430\u0440\u0443\u043c)? - \u0415\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u0436\u0435\u043d\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0441\u0442\u044c","description":"\u041f\u043e\u0447\u0435\u043c\u0443 \u043d\u0435\u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0436\u0435\u043d\u0449\u0438\u043d \u0442\u0430\u043a \u0442\u043e\u0448\u043d\u0438\u0442 \u0432 1 \u0442\u0440\u0438\u043c\u0435\u0441\u0442\u0440\u0435+? \u0413\u043e\u0440\u043c\u043e\u043d \u043f\u043e\u0434 \u043d\u0430\u0437\u0432\u0430\u043d\u0438\u0435\u043c GDF15 \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u0443\u0442\u0440\u0435\u043d\u043d\u044e\u044e \u0442\u043e\u0448\u043d\u043e\u0442\u0443 \u0438 \u0433\u0438\u043f\u0435\u0440\u0435\u043c\u0435\u0437\u0438\u0441 \u0433\u0440\u0430\u0432\u0438\u0434\u0430\u0440\u0443\u043c, \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/naturalwomanhood.org\/ru\/\u043f\u0440\u0438\u0447\u0438\u043d\u0430-\u0443\u0442\u0440\u0435\u043d\u043d\u0435\u0439-\u0442\u043e\u0448\u043d\u043e\u0442\u044b\/","og_locale":"ru_RU","og_type":"article","og_title":"What causes morning sickness (and hyperemesis gravidarum)?","og_description":"Cambridge University may have solved a question as old as time","og_url":"https:\/\/naturalwomanhood.org\/ru\/\u043f\u0440\u0438\u0447\u0438\u043d\u0430-\u0443\u0442\u0440\u0435\u043d\u043d\u0435\u0439-\u0442\u043e\u0448\u043d\u043e\u0442\u044b\/","og_site_name":"Natural Womanhood","article_publisher":"https:\/\/www.facebook.com\/NaturalWomanhood","article_published_time":"2024-04-11T13:00:00+00:00","article_modified_time":"2026-04-22T12:50:36+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg","type":"image\/jpeg"}],"author":"Jasmine Adams Piescik","twitter_card":"summary_large_image","twitter_creator":"@naturwomanhood","twitter_site":"@naturwomanhood","twitter_misc":{"\u041d\u0430\u043f\u0438\u0441\u0430\u043d\u043e \u0430\u0432\u0442\u043e\u0440\u043e\u043c":"Jasmine Adams Piescik","\u041f\u0440\u0438\u043c\u0435\u0440\u043d\u043e\u0435 \u0432\u0440\u0435\u043c\u044f \u0434\u043b\u044f \u0447\u0442\u0435\u043d\u0438\u044f":"7 \u043c\u0438\u043d\u0443\u0442"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#article","isPartOf":{"@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/"},"author":{"name":"Jasmine Adams Piescik","@id":"https:\/\/naturalwomanhood.org\/#\/schema\/person\/1d349d0b11b6928f0f91db832397c929"},"headline":"What causes morning sickness (and hyperemesis gravidarum)?","datePublished":"2024-04-11T13:00:00+00:00","dateModified":"2026-04-22T12:50:36+00:00","mainEntityOfPage":{"@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/"},"wordCount":1447,"commentCount":2,"publisher":{"@id":"https:\/\/naturalwomanhood.org\/#organization"},"image":{"@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage"},"thumbnailUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg","keywords":["morning sickness"],"articleSection":["Pregnancy & Childbirth","Pregnancy Health"],"inLanguage":"ru-RU","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/","url":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/","name":"\u0427\u0442\u043e \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u0443\u0442\u0440\u0435\u043d\u043d\u044e\u044e \u0442\u043e\u0448\u043d\u043e\u0442\u0443 (\u0438 \u0433\u0438\u043f\u0435\u0440\u0435\u043c\u0435\u0437\u0438\u0441 \u0433\u0440\u0430\u0432\u0438\u0434\u0430\u0440\u0443\u043c)? - \u0415\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u0436\u0435\u043d\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0441\u0442\u044c","isPartOf":{"@id":"https:\/\/naturalwomanhood.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage"},"image":{"@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage"},"thumbnailUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg","datePublished":"2024-04-11T13:00:00+00:00","dateModified":"2026-04-22T12:50:36+00:00","description":"\u041f\u043e\u0447\u0435\u043c\u0443 \u043d\u0435\u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0436\u0435\u043d\u0449\u0438\u043d \u0442\u0430\u043a \u0442\u043e\u0448\u043d\u0438\u0442 \u0432 1 \u0442\u0440\u0438\u043c\u0435\u0441\u0442\u0440\u0435+? \u0413\u043e\u0440\u043c\u043e\u043d \u043f\u043e\u0434 \u043d\u0430\u0437\u0432\u0430\u043d\u0438\u0435\u043c GDF15 \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u0443\u0442\u0440\u0435\u043d\u043d\u044e\u044e \u0442\u043e\u0448\u043d\u043e\u0442\u0443 \u0438 \u0433\u0438\u043f\u0435\u0440\u0435\u043c\u0435\u0437\u0438\u0441 \u0433\u0440\u0430\u0432\u0438\u0434\u0430\u0440\u0443\u043c, \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435.","breadcrumb":{"@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#breadcrumb"},"inLanguage":"ru-RU","potentialAction":[{"@type":"ReadAction","target":["https:\/\/naturalwomanhood.org\/morning-sickness-cause\/"]}]},{"@type":"ImageObject","inLanguage":"ru-RU","@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#primaryimage","url":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg","contentUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-scaled.jpeg","width":2560,"height":1707,"caption":"molar pregnancy, incomplete molar pregnancy, partial molar pregnancy, complete molar pregnancy, signs of molar pregnancy, molar pregnancy cancer"},{"@type":"BreadcrumbList","@id":"https:\/\/naturalwomanhood.org\/morning-sickness-cause\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/naturalwomanhood.org\/"},{"@type":"ListItem","position":2,"name":"What causes morning sickness (and hyperemesis gravidarum)?"}]},{"@type":"WebSite","@id":"https:\/\/naturalwomanhood.org\/#website","url":"https:\/\/naturalwomanhood.org\/","name":"\u0415\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u0436\u0435\u043d\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0441\u0442\u044c","description":"","publisher":{"@id":"https:\/\/naturalwomanhood.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/naturalwomanhood.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ru-RU"},{"@type":"Organization","@id":"https:\/\/naturalwomanhood.org\/#organization","name":"\u0415\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u0436\u0435\u043d\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0441\u0442\u044c","url":"https:\/\/naturalwomanhood.org\/","logo":{"@type":"ImageObject","inLanguage":"ru-RU","@id":"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Natural Womanhood"},"image":{"@id":"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/NaturalWomanhood","https:\/\/x.com\/naturwomanhood","https:\/\/www.instagram.com\/naturalwomanhood\/","https:\/\/www.linkedin.com\/company\/natural-womanhood\/","https:\/\/www.youtube.com\/channel\/UCt5gjuXYioYkx31Iq4tHLGg"]},{"@type":"Person","@id":"https:\/\/naturalwomanhood.org\/#\/schema\/person\/1d349d0b11b6928f0f91db832397c929","name":"\u0416\u0430\u0441\u043c\u0438\u043d \u0410\u0434\u0430\u043c\u0441 \u041f\u044c\u0435\u0448\u0438\u043a","image":{"@type":"ImageObject","inLanguage":"ru-RU","@id":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/jasmine-scaled.jpg","url":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/jasmine-scaled.jpg","contentUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/jasmine-scaled.jpg","caption":"Jasmine Adams Piescik"},"description":"\u0416\u0430\u0441\u043c\u0438\u043d \u041f\u0438\u0435\u0441\u0446\u0438\u043a \u0443\u0432\u043b\u0435\u043a\u043b\u0430\u0441\u044c \u0432\u043e\u043f\u0440\u043e\u0441\u0430\u043c\u0438 \u0444\u0435\u0440\u0442\u0438\u043b\u044c\u043d\u043e\u0441\u0442\u0438 \u0438 \u0435\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0433\u043e \u0436\u0435\u043d\u0441\u043a\u043e\u0433\u043e \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u044f \u0435\u0449\u0435 \u0432 \u043a\u043e\u043b\u043b\u0435\u0434\u0436\u0435 \u0431\u043b\u0430\u0433\u043e\u0434\u0430\u0440\u044f \u0440\u0430\u0437\u0433\u043e\u0432\u043e\u0440\u0430\u043c \u0441 \u0434\u0440\u0443\u0433\u0438\u043c\u0438 \u0436\u0435\u043d\u0449\u0438\u043d\u0430\u043c\u0438, \u0441\u043e\u0431\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439 \u0431\u043e\u0440\u044c\u0431\u0435 \u0441 \u0433\u043e\u0440\u043c\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u043c \u0434\u0438\u0441\u0431\u0430\u043b\u0430\u043d\u0441\u043e\u043c \u0438 \u0434\u043e\u043b\u0433\u043e\u043c\u0443 \u043f\u0443\u0442\u0438 \u043f\u043e\u0437\u043d\u0430\u043d\u0438\u044f \u0434\u0430\u0440\u0430 \u0441\u043e\u0431\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u0430. \u0421\u0435\u0439\u0447\u0430\u0441 \u043e\u043d\u0430 \u0436\u0438\u0432\u0435\u0442 \u0441 \u043c\u0443\u0436\u0435\u043c \u0432 \u0428\u0430\u0440\u043b\u043e\u0442\u0442\u0441\u0432\u0438\u043b\u043b\u0435, \u0448\u0442\u0430\u0442 \u0412\u0438\u0440\u0434\u0436\u0438\u043d\u0438\u044f, \u0433\u0434\u0435 \u043f\u043e\u043b\u0443\u0447\u0430\u0435\u0442 \u0441\u0442\u0435\u043f\u0435\u043d\u044c \u043c\u0430\u0433\u0438\u0441\u0442\u0440\u0430 \u0430\u043d\u0433\u043b\u0438\u0439\u0441\u043a\u043e\u0433\u043e \u044f\u0437\u044b\u043a\u0430 \u0438 \u043b\u044e\u0431\u0438\u0442 \u0445\u043e\u0434\u0438\u0442\u044c \u0432 \u043f\u043e\u0445\u043e\u0434\u044b, \u043f\u0440\u043e\u0431\u043e\u0432\u0430\u0442\u044c \u043d\u043e\u0432\u044b\u0435 \u0440\u0435\u0446\u0435\u043f\u0442\u044b \u0438 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u044c \u043c\u0435\u0441\u0442\u043d\u043e\u0435 \u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u043e \u043a\u043e\u0444\u0435\u0435\u043d \u0438 \u0432\u0438\u043d\u043e\u0434\u0435\u043b\u0435\u043d.","url":"https:\/\/naturalwomanhood.org\/ru\/author\/jadams\/"}]}},"taxonomy_info":{"category":[{"value":5185,"label":"Pregnancy & Childbirth"},{"value":5352,"label":"Pregnancy Health"}],"post_tag":[{"value":6155,"label":"morning sickness"}]},"featured_image_src_large":["https:\/\/naturalwomanhood.org\/wp-content\/uploads\/AdobeStock_195015325-1024x683.jpeg",1024,683,true],"author_info":{"display_name":"Jasmine Adams Piescik","author_link":"https:\/\/naturalwomanhood.org\/ru\/author\/jadams\/"},"comment_info":2,"category_info":[{"term_id":5185,"name":"Pregnancy & Childbirth","slug":"pregnancy-childbirth","term_group":0,"term_taxonomy_id":5185,"taxonomy":"category","description":"What the research does (and doesn't) say about how to have your healthiest pregnancy, labor, and birth, plus answers to your questions about unmedicated labor. ","parent":0,"count":167,"filter":"raw","term_order":"0","cat_ID":5185,"category_count":167,"category_description":"What the research does (and doesn't) say about how to have your healthiest pregnancy, labor, and birth, plus answers to your questions about unmedicated labor. ","cat_name":"Pregnancy & Childbirth","category_nicename":"pregnancy-childbirth","category_parent":0},{"term_id":5352,"name":"Pregnancy Health","slug":"pregnancy-health","term_group":0,"term_taxonomy_id":5352,"taxonomy":"category","description":"Hurray, baby's on the way! Here's how to have the healthiest pregnancy for you and baby. ","parent":5185,"count":67,"filter":"raw","term_order":"0","cat_ID":5352,"category_count":67,"category_description":"Hurray, baby's on the way! Here's how to have the healthiest pregnancy for you and baby. ","cat_name":"Pregnancy Health","category_nicename":"pregnancy-health","category_parent":5185}],"tag_info":[{"term_id":6155,"name":"morning sickness","slug":"morning-sickness-2","term_group":0,"term_taxonomy_id":6155,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","term_order":"0"}],"_links":{"self":[{"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/posts\/20413","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/users\/99"}],"replies":[{"embeddable":true,"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/comments?post=20413"}],"version-history":[{"count":0,"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/posts\/20413\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/media\/20414"}],"wp:attachment":[{"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/media?parent=20413"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/categories?post=20413"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/naturalwomanhood.org\/ru\/wp-json\/wp\/v2\/tags?post=20413"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}