{"id":23434,"date":"2025-09-20T08:00:29","date_gmt":"2025-09-20T13:00:29","guid":{"rendered":"https:\/\/naturalwomanhood.org\/?p=23434"},"modified":"2025-09-19T06:16:46","modified_gmt":"2025-09-19T11:16:46","slug":"intestino-estrogeno-cerebro-conexion","status":"publish","type":"post","link":"https:\/\/naturalwomanhood.org\/es\/gut-estrogen-brain-connection\/","title":{"rendered":"La conexi\u00f3n intestino-cerebro-estr\u00f3genos"},"content":{"rendered":"\n

<\/p>\n\n\n\n

Many readers of Natural Womanhood are familiar with the negative effects of combined oral contraceptives (COCs), commonly known as the Pill. COCs, in particular, contain both synthetic estrogen and progestin, vs the so-called \u201cmini-Pill<\/a>,\u201d which contains only progestin. We have written extensively about how these different contraceptive pills and devices work<\/a>, how the Pill affects your cycles<\/a>, and the numerous side effects<\/a> of contraceptives, one of which is mental health changes including depression<\/a>.<\/p>\n\n\n\n

But until recently, we didn\u2019t know why<\/em> birth control caused these mental health effects (which, by the way, are a risk for both COCs and the mini-Pill). But recent research<\/a> has found that the birth control pill can alter not only your hormonal balance, but also the balance of bacteria in your gut. This astounding link between the hormonal and gut changes behind the Pill and the combined effect on users\u2019 brains are finally providing clues to understand the Pill\u2019s effects on mental health.<\/p>\n\n\n\n

Your brain and your \u201csecond brain\u201d (aka your gut!)<\/span><\/h2>\n\n\n\n

At first glance, the gut and brain seem to have very different jobs. The former digests food and absorbs nutrients, while the latter processes thoughts, stores memories, and controls movement. Yet scientists now know they share many features and communicate more closely than once imagined. <\/p>\n\n\n\n

Both the gut and the brain are packed with complex networks of cells that send and receive signals, both rely on chemical messengers called neurotransmitters, and both influence how we feel physically and emotionally. In fact, the gut contains its own network of neurons lining the intestinal tract, known as the enteric nervous system<\/a>, which is sometimes called the \u201csecond brain<\/a>\u201d because it can operate independently while still talking to the brain through nerves and chemical signals [1].<\/p>\n\n\n\n

For over a decade now, scientists have been studying the enteric nervous system\u2013but each one of us is already familiar with its effects. If you\u2019ve ever had that feeling of \u201cbutterflies in your stomach,\u201d that\u2019s your second brain firing! <\/p>\n\n\n\n

Communication between the gut and the brain<\/span><\/h2>\n\n\n\n

The gut and brain are linked through what is called the gut-brain axis, a two-way communication system that uses nerves, hormones, and immune signals. One of the most important pathways is the vagus nerve, which acts like a high-speed information cable between the brain and the gut. The gut also produces and responds to many of the same neurotransmitters found in the brain, including serotonin and dopamine.<\/p>\n\n\n\n

Both the gut and brain are deeply influenced by the body\u2019s internal environment. Just as stress, diet, and infection can alter brain function, they can also shift the composition of the gut microbiome (or the community of helpful bacteria living in your gut) and change how the gut communicates with the brain. This shared sensitivity means that disruptions in gut health can affect mental health, and vice versa. Research into this connection is revealing how the gut\u2019s microbial community, chemical messengers, and immune signals can shape brain function, influencing mood, cognition, and even risk for neurological disorders [2,3].<\/p>\n\n\n\n

How does estrogen affect the gut?<\/span><\/h2>\n\n\n\n

This constant back-and-forth between the gut and brain does not happen in isolation. Hormones, particularly estrogen, also play an important role in the conversation. The gut microbiome helps regulate how much estrogen circulates in the body by producing enzymes that can activate or inactivate the hormone. In return, estrogen can change the makeup of the gut\u2019s microbial community, shaping which bacteria thrive [4]. This synergistic community is even given a fancy name\u2014the estrobolome<\/a>.<\/p>\n\n\n\n

The gut microbiome helps regulate how much estrogen circulates in the body by producing enzymes that can activate or inactivate the hormone. In return, estrogen can change the makeup of the gut\u2019s microbial community, shaping which bacteria thrive.<\/p><\/blockquote><\/figure>\n\n\n\n

Because estrogen affects brain regions involved in mood, memory, and cognition, any shifts in this gut-estrogen connection can also influence brain function. This three-way relationship between the gut, estrogen, and the brain is called the gut-estrogen-brain axis, and it is becoming a key focus for understanding how hormonal changes, gut health, and mental well-being are linked.<\/p>\n\n\n\n

The gut-estrogen-brain axis<\/span><\/h2>\n\n\n\n

The gut-estrogen-brain axis works through a constant feedback loop. Bacteria in the gut can reactivate estrogen, allowing it to travel through the bloodstream and reach various organs, including the brain. Estrogen influences brain function<\/a> by acting on areas that control mood, memory, and learning, and it can also affect the production of brain chemicals<\/a> such as serotonin and dopamine. <\/p>\n\n\n\n

At the same time, estrogen shapes which microbes live in the gut, influencing the balance of its bacterial community and how it communicates with the brain. When the gut microbiome becomes unbalanced, estrogen levels can shift<\/a>, potentially changing brain function and emotional health. Understanding this relationship is important because it means that changes to hormones, gut bacteria, or brain activity can ripple through the entire system.<\/p>\n\n\n\n

When the gut microbiome becomes unbalanced, estrogen levels can shift, potentially changing brain function and emotional health. <\/p><\/blockquote><\/figure>\n\n\n\n

Combined oral contraceptives introduce additional synthetic hormones<\/span><\/h2>\n\n\n\n

So what do oral contraceptives have to do with any of this? Recently, scientists have been interested in how oral contraceptive use might influence this gut-estrogen-brain connection. As stated earlier, combined oral contraceptives (COCs) contain synthetic forms of estrogen and progesterone which disrupt the body\u2019s natural hormone patterns; this is how they prevent pregnancy, as well as reduce symptoms of reproductive issues like uterine fibroids or heavy menstrual bleeding. But by changing the body\u2019s estrogen levels, COCs may also affect the gut microbiome and the signals it sends to the brain. The synthetic hormones can likewise alter the microbial community, which may change how much estrogen is available to circulate in the body. <\/p>\n\n\n\n

By changing the body\u2019s estrogen levels, COCs may also affect the gut microbiome and the signals it sends to the brain. The synthetic hormones can likewise alter the microbial community, which may change how much estrogen is available to circulate in the body. <\/p><\/blockquote><\/figure>\n\n\n\n

A recent article<\/a> on Contemporary OB\/GYN<\/em> summarized the research<\/a> on how COCs alter the gut microbiome and in turn affect mental health [5]. Interestingly, side effects of long term COCs include both<\/em> mood disorders (like depression) and gastrointestinal (GI) symptoms. And while you may only think of antibiotics as medicines that disrupt your gut, recent evidence suggests COCs also have the ability to disrupt the composition of bacteria living in your gut [5]. This led researchers to wonder whether the synthetic estrogen from the Pill was changing the gut microbiome and therefore affecting patients\u2019 moods. To do this, they compiled existing human and animal studies from a literature search in PubMed. <\/p>\n\n\n\n

Research suggests that women using hormonal contraceptives may experience changes in the diversity and activity of gut bacteria. COC users have reduced types of certain bacteria compared to non-users, and this disruption could have effects on various health outcomes. For example, there is a potential increased risk of developing or relapsing Crohn’s disease (CD) in women taking COCs, with risk increasing with the length of COC use and becoming insignificant upon discontinuation [6]. COCs may also alter intestinal permeability, a factor in CD pathogenesis (e.g., a study which examined sex differences in gastrointestinal (GI) barrier function found oral contraceptive users had the highest intestinal permeability when compared to women with natural menstrual cycles and men [7]). (This effect appears limited to estrogen-containing oral contraceptives, and does not include the progestin-only \u201cmini-Pill.\u201d) <\/p>\n\n\n\n

All these changes can affect gut barrier function, allowing inflammatory signals or neurotransmitter precursors to reach the brain more easily. Remember that the bacteria in the gut are responsible for producing many of the neurotransmitters that reach the brain, so this hormonal contraception-induced dysbiosis<\/a> can disrupt the balance of these neurotransmitters, potentially leading to mental health complications [5]. <\/p>\n\n\n\n

Additional research supporting the gut-estrogen-brain connection<\/span><\/h2>\n\n\n\n

Since a landmark Danish study published in 2016, which found a “small but real” increased risk of depression and antidepressant use with hormonal birth control (particularly in adolescents), we\u2019ve known the mental health risks of hormonal birth control are indeed real. The same research group also linked hormonal contraception use to increased suicide attempts and suicides, highlighting the extremely serious nature of the birth control-mental health connection [8]. But again, until recent research on the gut and its connection to the brain was discovered, the mechanism behind birth control\u2019s effects on mental health were unknown.  <\/p>\n\n\n\n

Further underscoring the connection between gut health and mental health, the Contemporary OB\/GYN<\/em> review article explained several animal studies that have shown that gut microbiome disruption or antibiotic-mediated dysbiosis can lead to depressive-like behaviors, which can be reversed by probiotics [9,10,11,12]. Likewise, a 2020 systematic review<\/a> of human studies found a correlation between decreased diversity in gut microbiome and depression diagnoses [13].<\/p>\n\n\n\n

However, conflicting research does exist: One longitudinal study following 10 healthy premenopausal women (aged 16-40) who started oral contraceptives between January 2015 and August 2018 demonstrated no significant change in the gut microbiome diversity or composition. However, this study did identify marginal changes in the function of the gut microbiome, and the type of COC used in this study was not evaluated [14].<\/p>\n\n\n\n

The bottom line<\/span><\/h2>\n\n\n\n

Changes in your \u201csecond brain\u201d could certainly explain why some individuals report mood changes, increased anxiety, or depressive symptoms while on birth control, though the effects vary widely between people. Not all studies find strong links, and many factors, like the type of contraceptive, hormone dose, and an individual\u2019s existing gut microbiome, likely influence outcomes.<\/p>\n\n\n\n

Still, the gut-estrogen-brain axis highlights how hormones, gut microbes, and brain function are closely interconnected. Hormonal birth control can disrupt this delicate balance by altering estrogen levels and changing gut microbial activity, and this may contribute to the mood changes some women experience.<\/p>\n\n\n\n

This is just one of several ways these medications may impact the body, alongside effects on gut microbes, hormone regulation, and reproductive health. While some people use these methods safely, the emerging research highlights the importance of considering natural fertility awareness methods, which avoid introducing synthetic hormones and allow the body\u2019s own systems to function without interference. <\/p>\n\n\n\n

References<\/span><\/h4>\n\n\n\n[1] Mayer EA, Tillisch K, Gupta A. Gut\/brain axis and the microbiota. J Clin Invest. 2015 Mar 2;125(3):926-38. doi: 10.1172\/JCI76304. Epub 2015 Feb 17. PMID: 25689247; PMCID: PMC4362231.<\/p>\n\n\n\n[2] Bonaz B, Bazin T, Pellissier S. The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis. Front Neurosci. 2018 Feb 7;12:49. doi: 10.3389\/fnins.2018.00049. PMID: 29467611; PMCID: PMC5808284.<\/p>\n\n\n\n[3] Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015 Apr-Jun;28(2):203-209. PMID: 25830558; PMCID: PMC4367209.<\/p>\n\n\n\n[4] Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: Physiological and clinical implications. Maturitas. 2017 Sep;103:45-53. doi: 10.1016\/j.maturitas.2017.06.025. Epub 2017 Jun 23. PMID: 28778332.<\/p>\n\n\n\n[5] Zim A, Bommareddy A. Estrogen-Gut-Brain Axis: Examining the Role of Combined Oral Contraceptives on Mental Health Through Their Impact on the Gut Microbiome. Cureus. 2025 Mar 28;17(3):e81354. doi: 10.7759\/cureus.81354. PMID: 40291231; PMCID: PMC12034237.<\/p>\n\n\n\n[6] Cornish JA, Tan E, Simillis C, Clark SK, Teare J, Tekkis PP. The risk of oral contraceptives in the etiology of inflammatory bowel disease: a meta-analysis. Am J Gastroenterol. 2008 Sep;103(9):2394-400. doi: 10.1111\/j.1572-0241.2008.02064.x. Epub 2008 Aug 5. PMID: 18684177.\/<\/p>\n\n\n\n

References Continued<\/span><\/h4>\n\n\n\n[7] Flood TR, Kuennen MR, Blacker SD, Myers SD, Walker EF, Lee BJ. The effect of sex, menstrual cycle phase and oral contraceptive use on intestinal permeability and ex-vivo monocyte TNF\u03b1 release following treatment with lipopolysaccharide and hyperthermia. Cytokine. 2022 Oct;158:155991. doi: 10.1016\/j.cyto.2022.155991. Epub 2022 Aug 6. PMID: 35944412.<\/p>\n\n\n\n[8] Skovlund CW, M\u00f8rch LS, Kessing LV, Lidegaard \u00d8. Association of Hormonal Contraception With Depression. JAMA Psychiatry. 2016 Nov 1;73(11):1154-1162. doi: 10.1001\/jamapsychiatry.2016.2387. Erratum in: JAMA Psychiatry. 2017 Jul 1;74(7):764. doi: 10.1001\/jamapsychiatry.2017.1446. PMID: 27680324.<\/p>\n\n\n\n[9] Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience. 2010 Nov 10;170(4):1179-88. doi: 10.1016\/j.neuroscience.2010.08.005. Epub 2010 Aug 6. PMID: 20696216.<\/p>\n\n\n\n[10] Li N, Wang Q, Wang Y, Sun A, Lin Y, Jin Y, Li X. Oral Probiotics Ameliorate the Behavioral Deficits Induced by Chronic Mild Stress in Mice via the Gut Microbiota-Inflammation Axis. Front Behav Neurosci. 2018 Nov 6;12:266. doi: 10.3389\/fnbeh.2018.00266. PMID: 30459574; PMCID: PMC6232506.<\/p>\n\n\n\n[11] Hayer SS, Hwang S, Clayton JB. Antibiotic-induced gut dysbiosis and cognitive, emotional, and behavioral changes in rodents: a systematic review and meta-analysis. Front Neurosci. 2023 Sep 1;17:1237177. doi: 10.3389\/fnins.2023.1237177. PMID: 37719161; PMCID: PMC10504664.<\/p>\n\n\n\n[12] Xu Q, Sun L, Chen Q, Jiao C, Wang Y, Li H, Xie J, Zhu F, Wang J, Zhang W, Xie L, Wu H, Zuo Z, Chen X. Gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal NLRP3-mediated neuroinflammation in a postpartum depression mouse model. Brain Behav Immun. 2024 Jul;119:220-235. doi: 10.1016\/j.bbi.2024.04.002. Epub 2024 Apr 8. PMID: 38599497.<\/p>\n\n\n\n[13] Barandouzi ZA, Starkweather AR, Henderson WA, Gyamfi A, Cong XS. Altered Composition of Gut Microbiota in Depression: A Systematic Review. Front Psychiatry. 2020 Jun 10;11:541. doi: 10.3389\/fpsyt.2020.00541. PMID: 32587537; PMCID: PMC7299157.<\/p>\n\n\n\n[14] Hua X, Cao Y, Morgan DM, Miller K, Chin SM, Bellavance D, Khalili H. Longitudinal analysis of the impact of oral contraceptive use on the gut microbiome. J Med Microbiol. 2022 Apr;71(4). doi: 10.1099\/jmm.0.001512. PMID: 35452382.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"\u00bfPodr\u00eda la p\u00edldora anticonceptiva afectar a tu salud mental cambiando tu intestino?","protected":false},"author":120,"featured_media":23438,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","csco_singular_sidebar":"","csco_page_header_type":"","csco_page_load_nextpost":"","csco_post_video_location":[],"csco_post_video_url":"","csco_post_video_bg_start_time":0,"csco_post_video_bg_end_time":0,"footnotes":""},"categories":[5366],"tags":[4056,6373],"class_list":{"0":"post-23434","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-hormone-imbalance","8":"tag-estrogen","9":"tag-gut-health","10":"cs-entry","11":"cs-video-wrap"},"acf":[],"yoast_head":"\nThe gut-brain-estrogen connection - Natural Womanhood<\/title>\n<meta name=\"description\" content=\"The link between hormonal and gut changes behind the Pill and the effect on users\u2019 brains are clues to the Pill\u2019s effects on mental health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/naturalwomanhood.org\/es\/intestino-estrogeno-cerebro-conexion\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The gut-brain-estrogen connection\" \/>\n<meta property=\"og:description\" content=\"Could the birth control pill affect your mental health by changing your gut?\" \/>\n<meta property=\"og:url\" content=\"https:\/\/naturalwomanhood.org\/es\/intestino-estrogeno-cerebro-conexion\/\" \/>\n<meta property=\"og:site_name\" content=\"Natural Womanhood\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NaturalWomanhood\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-20T13:00:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut-1024x683.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"683\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Elizabeth Wescott, PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@naturwomanhood\" \/>\n<meta name=\"twitter:site\" content=\"@naturwomanhood\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Elizabeth Wescott, PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"11 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/\"},\"author\":{\"name\":\"Elizabeth Wescott, PhD\",\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/person\/5677ce16990b113970544ffec24f53b4\"},\"headline\":\"The gut-brain-estrogen connection\",\"datePublished\":\"2025-09-20T13:00:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/\"},\"wordCount\":2149,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg\",\"keywords\":[\"estrogen\",\"gut health\"],\"articleSection\":[\"Hormone Imbalance\"],\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/\",\"url\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/\",\"name\":\"The gut-brain-estrogen connection - Natural Womanhood\",\"isPartOf\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg\",\"datePublished\":\"2025-09-20T13:00:29+00:00\",\"description\":\"The link between hormonal and gut changes behind the Pill and the effect on users\u2019 brains are clues to the Pill\u2019s effects on mental health.\",\"breadcrumb\":{\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage\",\"url\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg\",\"contentUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg\",\"width\":7934,\"height\":5292,\"caption\":\"birth control, gut health, birth control impacts gut health, gut health, brain health, second brain. birth control bad for gut\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/naturalwomanhood.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The gut-brain-estrogen connection\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/naturalwomanhood.org\/#website\",\"url\":\"https:\/\/naturalwomanhood.org\/\",\"name\":\"Natural Womanhood\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/naturalwomanhood.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/naturalwomanhood.org\/#organization\",\"name\":\"Natural Womanhood\",\"url\":\"https:\/\/naturalwomanhood.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Natural Womanhood\"},\"image\":{\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/NaturalWomanhood\",\"https:\/\/x.com\/naturwomanhood\",\"https:\/\/www.instagram.com\/naturalwomanhood\/\",\"https:\/\/www.linkedin.com\/company\/natural-womanhood\/\",\"https:\/\/www.youtube.com\/channel\/UCt5gjuXYioYkx31Iq4tHLGg\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/naturalwomanhood.org\/#\/schema\/person\/5677ce16990b113970544ffec24f53b4\",\"name\":\"Elizabeth Wescott, PhD\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/wescottheadshot.jpg\",\"url\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/wescottheadshot.jpg\",\"contentUrl\":\"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/wescottheadshot.jpg\",\"caption\":\"Elizabeth Wescott, PhD\"},\"description\":\"Elizabeth Wescott, Ph.D. is a scientist and educator with interests in immunology and science communication. During her PhD she studied how to improve immunotherapy treatments for breast cancer patients. She is particularly passionate about empowering her students, family, and community to ask questions and help them break down complex science topics. She lives in Nashville, TN with her husband and two daughters.\",\"url\":\"https:\/\/naturalwomanhood.org\/es\/author\/ewescott\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"La conexi\u00f3n intestino-cerebro-estr\u00f3geno - Natural Womanhood","description":"La relaci\u00f3n entre los cambios hormonales e intestinales detr\u00e1s de la p\u00edldora y el efecto en el cerebro de las usuarias son pistas sobre los efectos de la p\u00edldora en la salud mental.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/naturalwomanhood.org\/es\/intestino-estrogeno-cerebro-conexion\/","og_locale":"es_MX","og_type":"article","og_title":"The gut-brain-estrogen connection","og_description":"Could the birth control pill affect your mental health by changing your gut?","og_url":"https:\/\/naturalwomanhood.org\/es\/intestino-estrogeno-cerebro-conexion\/","og_site_name":"Natural Womanhood","article_publisher":"https:\/\/www.facebook.com\/NaturalWomanhood","article_published_time":"2025-09-20T13:00:29+00:00","og_image":[{"width":1024,"height":683,"url":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut-1024x683.jpeg","type":"image\/jpeg"}],"author":"Elizabeth Wescott, PhD","twitter_card":"summary_large_image","twitter_creator":"@naturwomanhood","twitter_site":"@naturwomanhood","twitter_misc":{"Escrito por":"Elizabeth Wescott, PhD","Tiempo de lectura":"11 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#article","isPartOf":{"@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/"},"author":{"name":"Elizabeth Wescott, PhD","@id":"https:\/\/naturalwomanhood.org\/#\/schema\/person\/5677ce16990b113970544ffec24f53b4"},"headline":"The gut-brain-estrogen connection","datePublished":"2025-09-20T13:00:29+00:00","mainEntityOfPage":{"@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/"},"wordCount":2149,"commentCount":0,"publisher":{"@id":"https:\/\/naturalwomanhood.org\/#organization"},"image":{"@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage"},"thumbnailUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg","keywords":["estrogen","gut health"],"articleSection":["Hormone Imbalance"],"inLanguage":"es","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/","url":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/","name":"La conexi\u00f3n intestino-cerebro-estr\u00f3geno - Natural Womanhood","isPartOf":{"@id":"https:\/\/naturalwomanhood.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage"},"image":{"@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage"},"thumbnailUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg","datePublished":"2025-09-20T13:00:29+00:00","description":"La relaci\u00f3n entre los cambios hormonales e intestinales detr\u00e1s de la p\u00edldora y el efecto en el cerebro de las usuarias son pistas sobre los efectos de la p\u00edldora en la salud mental.","breadcrumb":{"@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#breadcrumb"},"inLanguage":"es","potentialAction":[{"@type":"ReadAction","target":["https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/"]}]},{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#primaryimage","url":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg","contentUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut.jpeg","width":7934,"height":5292,"caption":"birth control, gut health, birth control impacts gut health, gut health, brain health, second brain. birth control bad for gut"},{"@type":"BreadcrumbList","@id":"https:\/\/naturalwomanhood.org\/gut-estrogen-brain-connection\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/naturalwomanhood.org\/"},{"@type":"ListItem","position":2,"name":"The gut-brain-estrogen connection"}]},{"@type":"WebSite","@id":"https:\/\/naturalwomanhood.org\/#website","url":"https:\/\/naturalwomanhood.org\/","name":"Natural Womanhood","description":"","publisher":{"@id":"https:\/\/naturalwomanhood.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/naturalwomanhood.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"es"},{"@type":"Organization","@id":"https:\/\/naturalwomanhood.org\/#organization","name":"Natural Womanhood","url":"https:\/\/naturalwomanhood.org\/","logo":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Natural Womanhood"},"image":{"@id":"https:\/\/naturalwomanhood.org\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/NaturalWomanhood","https:\/\/x.com\/naturwomanhood","https:\/\/www.instagram.com\/naturalwomanhood\/","https:\/\/www.linkedin.com\/company\/natural-womanhood\/","https:\/\/www.youtube.com\/channel\/UCt5gjuXYioYkx31Iq4tHLGg"]},{"@type":"Person","@id":"https:\/\/naturalwomanhood.org\/#\/schema\/person\/5677ce16990b113970544ffec24f53b4","name":"Doctora Elizabeth Wescott","image":{"@type":"ImageObject","inLanguage":"es","@id":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/wescottheadshot.jpg","url":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/wescottheadshot.jpg","contentUrl":"https:\/\/naturalwomanhood.org\/wp-content\/uploads\/wescottheadshot.jpg","caption":"Elizabeth Wescott, PhD"},"description":"La doctora Elizabeth Wescott es cient\u00edfica y pedagoga y se interesa por la inmunolog\u00eda y la comunicaci\u00f3n cient\u00edfica. Durante su doctorado estudi\u00f3 c\u00f3mo mejorar los tratamientos de inmunoterapia para pacientes con c\u00e1ncer de mama. Le apasiona especialmente capacitar a sus estudiantes, su familia y su comunidad para que hagan preguntas y les ayuden a desentra\u00f1ar temas cient\u00edficos complejos. Vive en Nashville, TN, con su marido y sus dos hijas.","url":"https:\/\/naturalwomanhood.org\/es\/author\/ewescott\/"}]}},"taxonomy_info":{"category":[{"value":5366,"label":"Hormone Imbalance"}],"post_tag":[{"value":4056,"label":"estrogen"},{"value":6373,"label":"gut health"}]},"featured_image_src_large":["https:\/\/naturalwomanhood.org\/wp-content\/uploads\/gut-1024x683.jpeg",1024,683,true],"author_info":{"display_name":"Elizabeth Wescott, PhD","author_link":"https:\/\/naturalwomanhood.org\/es\/author\/ewescott\/"},"comment_info":0,"category_info":[{"term_id":5366,"name":"Hormone Imbalance","slug":"hormone-imbalance","term_group":0,"term_taxonomy_id":5366,"taxonomy":"category","description":"How do you know you've got a hormonal imbalance? How can you optimize your hormonal health?","parent":5181,"count":32,"filter":"raw","term_order":"0","cat_ID":5366,"category_count":32,"category_description":"How do you know you've got a hormonal imbalance? How can you optimize your hormonal health?","cat_name":"Hormone Imbalance","category_nicename":"hormone-imbalance","category_parent":5181}],"tag_info":[{"term_id":4056,"name":"estrogen","slug":"estrogen","term_group":0,"term_taxonomy_id":4056,"taxonomy":"post_tag","description":"","parent":0,"count":5,"filter":"raw","term_order":"0"},{"term_id":6373,"name":"gut health","slug":"gut-health","term_group":0,"term_taxonomy_id":6373,"taxonomy":"post_tag","description":"","parent":0,"count":4,"filter":"raw","term_order":"0"}],"_links":{"self":[{"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/posts\/23434","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/users\/120"}],"replies":[{"embeddable":true,"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/comments?post=23434"}],"version-history":[{"count":0,"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/posts\/23434\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/media\/23438"}],"wp:attachment":[{"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/media?parent=23434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/categories?post=23434"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/naturalwomanhood.org\/es\/wp-json\/wp\/v2\/tags?post=23434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}