{"id":1327,"date":"2016-01-16T20:12:27","date_gmt":"2016-01-17T01:12:27","guid":{"rendered":"https:\/\/natural-womanhood.local\/?p=1327"},"modified":"2024-04-02T15:31:24","modified_gmt":"2024-04-02T20:31:24","slug":"puede-la-pildora-anticonceptiva-causar-defectos-de-nacimiento","status":"publish","type":"post","link":"https:\/\/naturalwomanhood.org\/es\/can-the-birth-control-pill-cause-birth-defects\/","title":{"rendered":"\u00bfPuede la p\u00edldora anticonceptiva provocar anomal\u00edas cong\u00e9nitas?"},"content":{"rendered":"<p>As January is <a href=\"http:\/\/www.nbdpn.org\/bdpm2016.php\">National Birth Defects Prevention Month<\/a>, you may have seen articles like <a href=\"http:\/\/time.com\/4169375\/birth-control-pill-not-linked-to-birth-defects-study\/\">this one<\/a> in Time Magazine claiming that birth control pills are not linked to birth defects. It\u2019s because a recent <a href=\"http:\/\/www.bmj.com\/content\/352\/bmj.h6712\">large scale study from Denmark<\/a> just came out with these conclusions. But this study is not telling the whole story and the news distracts us from the real problem. In fact, it\u2019s missing the mark on serious effects of the Pill\u2019s chemistry on the fetus.\u00a0Here is the rest of the story: babies whose mothers have been on the Pill and are thus exposed to synthetic estrogen may not show the birth defects researched in the Danish study, like a\u00a0congenital heart anomaly\u00a0or a missing limb, but are likely to\u00a0suffer longer term effects such as prostate cancer, breast cancer, or low sperm counts. Yet there is a deafening silence and lack of research on this inconvenient truth.<\/p>\n<p>Three years ago, our daughter created <a href=\"https:\/\/www.youtube.com\/watch?v=rnEQeTSqdBQ\">a very clever animation video<\/a> as part of a communications project where she made a statement that the Pill was linked to prostate cancer, which at first glance sounds like an odd concept. Last summer, this allegation was clarified for me when I attended the <a href=\"http:\/\/www.contraceptiveconundrum.com\/#intro\">Contraceptive Conundrum Conference<\/a> in Washington DC and heard a presentation by Frederick Vom Saal, PhD. Dr. Vom Saal is a developmental biologist and professor of biology at the University of Missouri-Columbia, Miss. He is a fellow of the American Association for the Advancement of Science. The National Institute of Health funds his research. He was <a href=\"http:\/\/www.pbs.org\/wgbh\/pages\/frontline\/shows\/nature\/interviews\/vomsaal.html\">interviewed by PBS<\/a> in 1998 on his research showing the relationship between estrogen found in the environment and prostate diseases.<\/p>\n<h2 id=\"what-history-and-world-health-data-tell-us-about-birth-control-and-birth-defects\">What history and world health data tell us about birth control and birth defects<\/h2>\n<p>We must learn from history. Vom Saal\u2019s introduced his presentation by reminding us of<a href=\"https:\/\/en.wikipedia.org\/wiki\/Diethylstilbestrol\"> the DES scandal<\/a>. Between 1940 and 1971, millions of women were prescribed a drug called DES as a way to prevent miscarriages. In 1971, this drug was found to cause a 40-fold increase in risk of vaginal or cervical cancer in the teen or adult daughters of these women. A major lesson from these tragic events was that when pregnant women absorbed certain forms of estrogen, they exposed their fetus to small amounts of the hormone and it would have grave and irreversible health consequences for their baby. It also showed that these consequences would only show up much later in the child\u2019s life.<\/p>\n<p>What happened to these women had been previously demonstrated on mice. \u201cThere was data that was ignored because it was animal research that wasn\u2019t relevant to human health,\u201d reports Vom Saal. But the reality of the syndrome showed the contrary: the animal research was predictive of the human impact. \u201cWe know that mouse cells are essentially identical to human cells in the way that they respond to these hormones,\u201c said Vom Saal. Such biological evidence allows him to correlate the results observed in his research on mice and what we all observe in public health statistics.<\/p>\n<p>Indeed, if we focus only\u00a0on men\u2019s health, which is Vom Saal\u2019s research field, we find two areas are of major public health concern:<\/p>\n<ul>\n<li>The prevalence of prostate cancer: prostate cancer is <a href=\"http:\/\/globocan.iarc.fr\/old\/FactSheets\/cancers\/prostate-new.asp\">the second most common cancer<\/a> in men, accounting for 15% of the cancers diagnosed in men, with almost 70% of the cases (759,000 per year) occurring in more developed regions (which are also the main users of the Pill).<\/li>\n<li>The alarming rate of decreased of sperm count, a major cause of infertility. <a href=\"http:\/\/ispub.com\/IJU\/2\/1\/7519\">This article<\/a> presents the dramatic, accelerating drop in sperm count reported in some studies: 50% since 1950 and 25% just in the past 20 years. (<a href=\"https:\/\/naturalwomanhood.org\/why-is-male-reproductive-health-declining\/\">read here<\/a> for more on this topic)<\/li>\n<\/ul>\n<h2 id=\"the-science-behind-the-facts\">The science behind the facts<\/h2>\n<p>While traditional toxicology studies look at elevated levels of chemicals and their relationship to diseases during the lifetime of the person, Vom Saal research shows that in fact very small amounts of estrogen impact the fetus permanently, showing its effects during the rest of the person\u2019s life, in ways that cannot be corrected. Further, he claims that such changes could be multi-generational.<\/p>\n<p>Vom Saal observed that male mice from the same litter could experience very minor differences in estrogen hormone exposure during gestation that would lead to major differences in the fully developed\u00a0mice: the size of the scrotum and the penis, the libido, and the size of the prostate were all clearly affected.<\/p>\n<p>This discovery led to further research on mice. Vom Saal\u00a0was able to show that by exposing the fetus to very small amounts of estradiol estrogen (also famously known as EE) at critical times of development, the resulting males\u2019 prostates had doubled in size compared to the control sample. Later, when exposing the adults to normal hormonal changes due to age, 100% of these males got prostate cancer.<\/p>\n<p>\u201cWe see dramatic change in the sprouting of glands within the fetal prostate. We see changes in testicular sperm production. We see changes in the structure of the endocrine control region in the brain, which is accompanied by changes in sex behavior, aggression, the way these animals behave towards infants, their whole social interaction, the way they age, the time that they enter puberty, the age at which they cease reproduction. It changes their entire life history, and these changes are capable of occurring at very low levels of hormones,\u201d reports Vom Saal in his 1998 PBS interview about environmental EE. <a href=\"http:\/\/humrep.oxfordjournals.org\/content\/16\/5\/988.short\">In this study<\/a> published in the journal <em>Human Reproduction<\/em>, exposure to a small dose of EE (from 0.002 to 2 \u00b5g\/kg\/day) during the early phase of gestation led to an increase in the prostate weight, a change in its response to hormones, and a significant reduction in sperm count.<\/p>\n<p>Vom Saal claims that the dose of EE in the Pill, which is about 0.3 \u00b5g\/kg\/day, has similar potential effects. Not only does it change the physiology of the person\u2019s reproductive system, but it also affects the way the cells in the organs will respond to hormonal changes in the future. That\u2019s where the higher risk of cancer comes from. That\u2019s how the DES daughters syndrome happened. Could it be why prostate cancer is so prevalent or sperm count reaching crisis levels? \u00a0Vom Saal along with other scientists<a href=\"#_edn1\" name=\"_ednref1\">[i]<\/a> are certainly making a strong case for it.<\/p>\n<h2 id=\"what-is-the-exposure-with-the-pill\">What is the exposure with the Pill?<\/h2>\n<p>The big question for women on the Pill is when does it likely happen, so that one would know when to quit hormonal contraceptives to minimize the chance of exposure? The answer is quite broad: before, during and after conception. According to Dr. Vom Saal, the impact can start as soon as the egg starts developing in the ovaries, which is 2 \u00bd to 3 months before conception: \u201cyou are at a stage of development of the ovocite when it\u2019s absolutely clear that hormonal insults to the mother can impact that process.\u201d Exposure during conception is pretty common. About 9% of women on oral contraceptive pills get pregnant. In the US, it represents about 1 million babies a year. Worldwide about 10 million. To make matters worse, it takes at least a couple of weeks for a\u00a0woman to know she is pregnant, and some women won&#8217;t realize they are pregnant for some time simply because the pill is already suppressing their periods, which will potentially extend the duration of the exposure.<\/p>\n<p>Dr. Vom Saal&#8217;s focus is on the male reproductive system. There are other areas and organs that are very likely affected in a similar fashion. The same process applies to female breast tissues and their response to estrogen, which can lead to <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3140020\/\">breast cancer<\/a> later in the life of babies exposed.<\/p>\n<p>The CDC provides a <a href=\"http:\/\/www.cdc.gov\/ncbddd\/birthdefects\/prevention.html\">list of measures to prevent birth defect<\/a>s, from eating healthy and avoiding harmful chemical substances to taking folic acid supplements. But they don\u2019t warn about EE exposure from birth control. There is a deafening silence on these questions. \u201cIf anybody was looking, which the medical community does not want anybody to do because there is just panic over this, you would see the same kind of data. There is a massive uncontrolled experiment going on and nobody is collecting this data,\u201d stated Dr. Vom Saal. Before we hurry and say it\u2019s safe, have we really made sure?<\/p>\n<p><em>References<\/em><\/p>\n<p><a href=\"#_ednref1\" name=\"_edn1\">[i]<\/a> <a href=\"http:\/\/www.pnas.org\/content\/102\/19\/7014\">Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra<\/a>. Communicated by Howard A. Bern, University of California, Berkeley, CA, March 28, 2005 (received for review November 2, 2004)<\/p>\n<p><a href=\"http:\/\/ruderman.haps.hms.harvard.edu\/sites\/ruderman.haps.hms.harvard.edu\/files\/Mathews%20EE2%20penis%202010.pdf\">TOXICOLOGICAL SCIENCES<\/a> 112(2), 331\u2013343 (2009) Mal-Development of the Penis and Loss of Fertility in Male Rats Treated Neonatally with Female Contraceptive 17a-Ethinyl Estradiol: A Dose-Response Study and a Comparative Study with a Known Estrogenic Teratogen Diethylstilbestrol. Ensa Mathews et Al<\/p>\n<p><a href=\"http:\/\/bmjopen.bmj.com\/content\/1\/2\/e000311.full\">BMJ Open 2011<\/a> Occupational &amp; environmental medicine, <em>Oral contraceptive use is associated with prostate cancer: an ecological study<\/em>, by David Margel, Neil E Fleshner. See also the <a href=\"http:\/\/bmjopen.bmj.com\/content\/2\/3\/e000311corr1\">correction here<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Como enero es el Mes Nacional de la Prevenci\u00f3n de los Defectos de Nacimiento, es posible que haya visto art\u00edculos como este en Time...","protected":false},"author":2,"featured_media":1331,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","csco_singular_sidebar":"","csco_page_header_type":"","csco_page_load_nextpost":"","csco_post_video_location":[],"csco_post_video_url":"","csco_post_video_bg_start_time":0,"csco_post_video_bg_end_time":0,"footnotes":""},"categories":[5183,5260],"tags":[5571,4456,5449],"class_list":{"0":"post-1327","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-birth-control-issues","8":"category-general-health-risks","9":"tag-birth-control-side-effects","10":"tag-healthy-pregnancy","11":"tag-mens-health-fertility","12":"cs-entry","13":"cs-video-wrap"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can the birth control pill cause birth defects? 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